世界杯下注网站-2022世界杯下注网站

世界杯下注网站-2022世界杯下注网站

Medication Use & Patient Safety

“我们的工作为患者和医生提供了药物使用结果的证据,包括有害的和有益的,以帮助他们在处方药物使用方面做出明智的个人决定。.”

Sascha Dublin, MD, PhD
凯撒永久华盛顿健康世界杯下注网站所高级世界杯下注网站
华盛顿永久医疗集团内科医师

Research overview

美国人使用的处方药比以往任何时候都多. Consequently, they’re coping with more side effects, drug interactions, and costs, especially if they’re using multiple medications. 凯撒永久华盛顿健康世界杯下注网站所(KPWHRI)的科学家们正站在回答这些问题的前沿. 我们正在世界杯下注网站药物在现实环境中的有益和有害影响, 创新管理和监测药物使用的更好方法.

世界杯下注网站所为监测药物安全的国家倡议作出贡献,并提供信息,帮助医生和患者权衡各种处方药的风险和益处.

KPWHRI药物使用和患者安全世界杯下注网站的资助者包括 Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, the Patient-Centered Outcomes Research Institute, and other sources. A few projects include:

  • Studying whether commonly used medications, including oral contraceptives, 与发生COVID-19感染或严重疾病的风险有关
  • 探索阿片类药物误用、滥用和成瘾的患者和临床危险因素
  • 评估长期服用大剂量阿片类药物的患者在不影响疼痛管理和生活质量的情况下成功减少其使用的干预措施
  • 主动监测医疗产品通过 FDA Sentinel Initiative
  • Studying medication safety for pregnant people and older adults
  • Monitoring vaccine safety and effectiveness
  • Investigating how medications affect risk of cognitive decline and dementia in late life
  • 向患者和医疗服务提供者告知风险, and alternatives to, 常用的药物可能会导致跌倒, including over-the-counter antihistamines

Recent publications on Medication Use & Patient Safety

刘国强,李国强,李国强,李国强,李国强,李国强,李国强. 对阿得拉的预期影响主观情绪和药物效果,而不考虑同时摄入咖啡因:一项随机对照试验. Psychopharmacology (Berl). 2023 Sep 23. doi: 10.1007/s00213-023-06467-8. Online ahead of print. PubMed

陈毅,Loucks AR, Sullivan SD, Pearson SD, Kent D,杨凯. 为商业健康计划设计基于价值的处方:糖尿病药物的模拟案例世界杯下注网站. Value Health. 2023 Feb 14:S1098-3015(23)00053-0. doi: 10.1016/j.jval.2023.02.004. [Epub ahead of print]. PubMed

Tchesnokova V, Larson L, Basova I, Sledneva Y, Choudhury D, Heng J, Solyanik T, Bonilla T, Pham S, Schartz E, Madziwa L, Holden E, Weissman S, Ralston J, Sokurenko E. 尽管抗生素处方减少,但耐氟喹诺酮类大肠杆菌肠道携带率增加. Res Sq. 2023 Jan 12;rs.3.rs-2426668. doi: 10.21203/rs.3.rs-2426668/v1. Preprint. PubMed

Chen C, Hennessy S, Brensinger CM, Bilker WB, Dublin S, Chung SP, Horn JR, Bogar KF, Leonard CE. 抗抑郁药-药物-药物相互作用与非故意创伤性损伤相关:筛选现实世界数据中的信号. Clin Transl Sci. 2022 Nov 22. doi: 10.1111/cts.13452 [Epub ahead of print] PubMed

Carrell DS, Gruber S, Floyd JS, Bann MA, Cushing-Haugen KL, Johnson RL, Graham V, Cronkite DJ, Hazlehurst BL, Felcher AH, Bejan CA, Kennedy A, Shinde M, Karami S, Ma Y, Stojanovic D, Zhao Y, Ball R, Nelson J. 使用自然语言处理和机器学习改进医疗产品安全监测中过敏反应的识别方法. Am J Epidemiol. 2022 Nov 4:kwac182. doi: 10.1093/aje/kwac182. [Epub ahead of print]. PubMed

Researchers in Medication Use & Patient Safety

Sascha Dublin, MD, PhD

Senior Investigator
206-287-2870
Sascha.Dublin@kp.org

Curriculum vitae (CV)

Jessica Chubak, PhD

Senior Investigator
206-287-2556
Jessica.Chubak@kp.org

Curriculum vitae (CV)

Andrea J. Cook, PhD

Senior Biostatistics Investigator
206-287-4257
Andrea.J.Cook@kp.org

Curriculum vitae (CV)

Rita Mangione-Smith, MD, MPH

Executive Director and Senior Investigator, KPWHRI; Vice President for Research and Health Care Innovation, 2022世界杯下注网站 Washington
206-287-2988
Rita.M.Mangione-Smith@kp.org

Curriculum vitae (CV)

Jennifer C. Nelson, PhD

Director, Biostatistics; Senior Investigator
206-287-2004
Jen.Nelson@kp.org

Curriculum vitae (CV)

David E. Arterburn, MD, MPH

Senior Investigator
206-287-4610
David.E.Arterburn@kp.org

Curriculum vitae (CV)

Susan M. Shortreed, PhD

Senior Biostatistics Investigator
206-287-2088
Susan.M.Shortreed@kp.org

Curriculum vitae (CV)

Lisa A. Jackson, MD, MPH

Senior Investigator
Lisa.A.Jackson@kp.org

Curriculum vitae (CV)

Karen Wernli, PhD

Senior Investigator
206-287-2934
Karen.J.Wernli@kp.org

Curriculum vitae (CV)

Onchee Yu, MS

Principal Collaborative Biostatistician
206-287-2389
Onchee.Yu@kp.org

Curriculum vitae (CV)

Rod L. Walker, MS

Senior Collaborative Biostatistician
206-287-2895
Rod.L.Walker@kp.org

Curriculum vitae (CV)

Robert D. Wellman, MS

Senior Collaborative Biostatistician
206-287-2557
Robert.D.Wellman@kp.org

Curriculum vitae (CV)

Gaia Pocobelli, PhD

Senior Collaborative Scientist
206-287-2914
Gaia.S.Pocobelli@kp.org

Curriculum vitae (CV)

David S. Carrell, PhD

Associate Investigator
206-287-2705
David.S.Carrell@kp.org

Curriculum vitae (CV)

Laura Harrington, PhD, MPH

Assistant Investigator
206-287-2066
Laura.B.Harrington@kp.org

Curriculum vitae (CV)

Jennifer F. Bobb, PhD

Associate Biostatistics Investigator
206-287-2190
Jennifer.F.Bobb@kp.org

Curriculum vitae (CV)

Weiwei Zhu, MS

Senior Collaborative Biostatistician
206-442-5215
Weiwei.Zhu@kp.org

Curriculum vitae (CV)

Paige D. Wartko, PhD, MPH

Collaborative Scientist
206-442-5230
Paige.D.Wartko@kp.org

Curriculum vitae (CV)

Maricela Cruz, PhD

Assistant Biostatistics Investigator
206-287-2878
Maricela.F.Cruz@kp.org

Curriculum vitae (CV)

Brian D. Williamson, PhD

Assistant Biostatistics Investigator
206-287-2024
Brian.D.Williamson@kp.org

Curriculum vitae (CV)

Noorie Hyun, PhD

Assistant Biostatistics Investigator
Noorie.Hyun@kp.org

Curriculum vitae (CV)

Laurel Hansell, MA, MPH

Collaborative Scientist
laurel.d.hansell@kp.org

Curriculum vitae (CV)

Jess Mogk, MPH

Collaborative Scientist
Jessica.M.Mogk@kp.org

Curriculum vitae (CV)

Annie Piccorelli, PhD

Senior Collaborative Biostatistician
Annie.V.Piccorelli@kp.org

Affiliate researchers

Susan Heckbert, MD, PhD
University of Washington (UW) Department of Epidemiology; UW Cardiovascular Health Research Unit

David Siscovick, MD, MPH
UW Department of Medicine; UW Department of Epidemiology; UW Cardiovascular Health Research Unit

Leslie Spangler, PhD
Amgen